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5-nitro-2-(3-phenylpropylamino)-benzoic acid (NPPB)

Substrate Information
Inhibitor Information
Clinical Drug-drug Interactions

In Vitro Substrates

No substrate information.


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In Vitro Inhibitors

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Inhibitor IC50 (μM) Ki (μM) Substrate used Cell System Reference
ABCC5 MRP5 5-nitro-2-(3-phenylpropylamino)-benzoic acid (NPPB) 2 5-fluorodeoxyuridine monophosphate MRP5-expressing HEK293 vesicles Pratt, 2005
ABCC5 MRP5 5-nitro-2-(3-phenylpropylamino)-benzoic acid (NPPB) 0.102 Carboxydichlorofluorescein MRP5-expressing HEK293 vesicles Pratt, 2006

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Clinical Drug-Drug Interactions

No drug-drug interaction information.


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