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Cefadroxil

Substrate Information
Inhibitor Information
Clinical Drug-drug Interactions

In Vitro Substrates

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Km (μM) Cell System Reference
SLC15A1 PEPT1 ND HeLa-PEPT1 Knutter, 2009
SLCO1B3 OATP1B3, OATP8 4.15 oocytes-OATP1B3 Nakakariya, 2008

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In Vitro Inhibitors

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Inhibitor IC50 (μM) Ki (μM) Substrate used Cell System Reference
ABCC2 MRP2, cMOAT Cefadroxil >133 Estradiol-17beta-glucuronide Sf9 cell membrane vesicles Morgan, 2013
ABCC3 MRP3 Cefadroxil >133 Estradiol-17beta-glucuronide Sf9 cell membrane vesicles Morgan, 2013
ABCC4 MRP4 Cefadroxil >133 Estradiol-17beta-glucuronide Sf9 cell membrane vesicles Morgan, 2013
SLC22A6 OAT1 Cefadroxil 6140 Prostaglandin F2-alpha S2-OAT1 Khamdang, 2003
SLC22A8 OAT3 Cefadroxil 8620 Prostaglandin F2-alpha S2-OAT3 Khamdang, 2003
ABCB11 BSEP Cefadroxil >133 Taurocholate Sf9 cell membrane vesicles Morgan, 2013

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Clinical Drug-Drug Interactions

No drug-drug interaction information.


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