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Mevinolin

Substrate Information
Inhibitor Information
Clinical Drug-drug Interactions

In Vitro Substrates

No substrate information.


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In Vitro Inhibitors

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Inhibitor IC50 (μM) Ki (μM) Substrate used Cell System Reference
SLCO1B1 OATP1B1, OATP-C, OATP2, LST-1 Mevinolin 6.1 Estradiol-17beta-glucuronide CHO-OATP1B1 Gui, 2008
SLCO1B3 OATP1B3, OATP8 Mevinolin 92.6 Estradiol-17beta-glucuronide CHO-OATP1B3 Gui, 2008
SLCO1B1 OATP1B1, OATP-C, OATP2, LST-1 Mevinolin 12.7 Estradiol-17beta-glucuronide CHO-OATP1B1 Gui, 2009

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Clinical Drug-Drug Interactions

No drug-drug interaction information.


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