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Tangeretin

Substrate Information
Inhibitor Information
Clinical Drug-drug Interactions

In Vitro Substrates

No substrate information.


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In Vitro Inhibitors

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Inhibitor IC50 (μM) Ki (μM) Substrate used Cell System Reference
SLCO2B1 OATP2B1, OATP-B Tangeretin 1.6 4',5'-dibromofluorescein HEK293 cells Bajraktari-Sylejmani, 2020
SLCO1B1 OATP1B1, OATP-C, OATP2, LST-1 Tangeretin 4.8 8-fluorescein-cAMP HEK293 cells Bajraktari-Sylejmani, 2020
SLCO1B3 OATP1B3, OATP8 Tangeretin 5.6 8-fluorescein-cAMP HEK293 cells Bajraktari-Sylejmani, 2020

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Clinical Drug-Drug Interactions

No drug-drug interaction information.


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