UCSF home page About UCSF UCSF Medical Center
UCSF home page | About UCSF | UCSF Medical Center

Skip to TransPortal content

Decrease the text sizeRestore original text sizeIncrease the text size Enlarge Text
Click to increase the text size. Restore Text
Click to restore original text size. Reduce Text
Click to decrease the text size.
Transporter Database banner  
Decrease the text size | Restore text size | Increase the text size
 Text Sizer image
Home About and More Information Transporter Data Index
Search:  
 

Trazodone

Substrate Information
Inhibitor Information
Clinical Drug-drug Interactions

In Vitro Substrates

No substrate information.


Back to top

In Vitro Inhibitors

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Inhibitor IC50 (μM) Ki (μM) Substrate used Cell System Reference
SLC22A3 OCT3 Trazodone 5.2 4-(4-dimethylamino)styryl-N-methylpyridinium (ASP+) HEK293-OCT3 Chen, 2022
SLC22A8 OAT3 Trazodone 2.94 6-carboxyfluorescein HEK293-OAT3 Zou, 2021
SLC22A6 OAT1 Trazodone 19.9 6-carboxyfluorescein HEK293-OAT1 Zou, 2021
ABCC3 MRP3 Trazodone >133 Estradiol-17beta-glucuronide Sf9 cell membrane vesicles Morgan, 2013
ABCC4 MRP4 Trazodone >133 Estradiol-17beta-glucuronide Sf9 cell membrane vesicles Morgan, 2013
SLC22A3 OCT3 Trazodone 2.5 Metformin HEK293-OCT3 Chen, 2022
ABCB11 BSEP Trazodone >133 Taurocholate Sf9 cell membrane vesicles Morgan, 2013

Back to top

Clinical Drug-Drug Interactions

No drug-drug interaction information.


Back to top

Contact us | Glossary

Blue banner