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Verapamil (Racemic)

Substrate Information
Inhibitor Information
Clinical Drug-drug Interactions

In Vitro Substrates

No substrate information.


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In Vitro Inhibitors

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Inhibitor IC50 (μM) Ki (μM) Substrate used Cell System Reference
ABCB1 MDR1, P-gp Verapamil (Racemic) 4.8 Paclitaxel MES-SA/DX5 cells Lee, 2003
SLC22A1 OCT1 Verapamil (Racemic) 2.9 Tetraethylammonium HeLa-OCT1 Zhang, 1998
SLC22A1 OCT1 Verapamil (Racemic) 1.23 YM155 HEK293-OCT1 Minematsu, 2010

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Clinical Drug-Drug Interactions

No drug-drug interaction information.


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